paediatrics Brussels 17

Lymphnode involvement in

Hodgkin`s disease:

• Supradiaphgramatic lymphadenopathy (cervical +++) : 80% of HD cases ; usually non inflammatory, painless, ferm, sometimes tender

Mauch, Cancer 1993;71:2062

• Mediastinal involvement (leading to symptoms : dyspnea, cough, …) : > 50% of HD cases (up to 75% of HD) – 1/3 if < 10 y.

– > 2/3 if adolescents – Rarely isolated (< 5%)

Crnkovich, JCO 1987:5(7)1041

• isolated infradiaphragmatic involvement : < 5%