paediatrics Brussels 17

Early stages of Hodgkin´s Disease

COG relative Dose reduct.

COG absolute Dose reduct.

V5 Volume CCSS

V5 Volume COG

Mean dose reduction at OAR Influence Volume vs dose

breast

83.5%

15.5Gy

61%

17%

40% smaller volumes

heart

68.6%

22.9 Gy

99%

61%

24% smaller volumes

lung

61.0%

15.0 Gy

12% smaller volumes

thyroid 49.0%

20.7 Gy

Dose reduction

The influence of a lower prescription dose versus a smaller treatment varies and depend on the tissue and disease stage • Breast profits most from smaller irradiated volume