paediatrics Brussels 17

Rhabdomyosarcoma

• Accounts for about 3-4% of malignant disease in children < 15 years • Most common soft tissue sarcoma in children • Annual incidence of RMS is 4.4 per million in white children and 1.3 per million in black children • A small proportion associated with genetic conditions (Li- Fraumeni syndrome, NF-1, Beckwith-Wiedemann syndrome)