paediatrics Brussels 17

Medulloblastoma - MRI

• Iso to mildly T1 hypointense/mixed T2 SI • Grows circumferentially to fill/obliterate 4V • Doesn’t usually extend out through foramen of Luschka • More aggressive lesions invade brainstem and/or adjacent cerebellar parenchyma • Haemorrhage, necrosis or cystic change in 20-50% • Generally strong or heterogeneous enhancement • DWI: typically restricted diffusion (dark on ADC maps) • MRS: elevated Choline and Taurine, low NAA