2016_Head & Neck COURSE BOOK

HISTOLOGY

NEW FINDINGS IN ESTABLISHED ENTITIES HIGH GRADE TRANSFORMATION OF ADENOID CYSTIC CARCINOMA Chromosomal translocation leading to over expression of MYB-NFIB fusion proteins controlling proliferation apoptosis, differentiation

DUCTAL CARCINOMA Overexpression of estrogen receptor Beta-isoform (73%) Overexpression of androgen receptor (more than 90%)

C l i n i c a l a c t i v i t y o f a n d r o g e n deprivation therapy in patients with me t as t a t i c / r e l apsed ARpos i t i ve salivary gland cancers L. Locati, F. Perrone, B. Cortelazzi, et al. Head & Neck (accepted article 2014) mercoledì 29 giugno 16

2014