Advanced Brachytherapy Physics - Vienna 2016

Examples for real dose‐response curves and effect of random uncertainty for total dose (EQD2)

Uncertainties of physical fraction dose

Patient B

R=f(D+DD)

Patient A

t d expec e response

R

translated to total dose EQD2

R=f(D-DD)

R=f(D-+DD) R=f(D) R=f(D-DD)

Patient B

to uncertainty in response probability

expected dose D

D DD -

D+DD

P ti t A a en

target

OAR