Advanced Brachytherapy Physics - Vienna 2016

Effect of random dosimetric uncertainty (SD) on mean simulated dose response data for OAR D ‐ 2cm³  Simulated patient data Calculated dose-response curve for (S SS) simulated patients P

SD 10% per BT fraction SD 20% SD 30%

Increasing offset with increasing dose and increasing random dosimetric uncertainty: 2-3 % for SD 20% and 30% around rectum dose constraint level

Nesvacil et al. 2016, R&O, submitted