BCRB 2018
19/09/2018
Local tumor control
Basic clinical radiobiology
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Ex-vivo assays
• Clonogenic assays (plating assays) • Tumors are excised, reduced to single cells and grown in a test environment • Provide a direct measure of the surviving fraction of clonogenic cells. • Limitation: relationship between clonogens (in test environment) and stem cells (in situ) is uncertain.
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