BCRB 2018
19/09/2018
Clonogenic cell survival: ex vivo
cell suspension
tumor
X
culture dish
Mouse with tumor
colonies after in vitro growth
X
CON
Ex-vivo assays
• Culturing as organoids • Tumors are excised, reduced to single cells, and grown in 3D matrix • Measurement of tumor stem cells • Show potential to differentiate in all tumor subtype cells • Lack of environmental factors and vascularisation
22
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