BCRB 2018

19/09/2018

Dose scheduling for RT+IT combinations

Dovedi et al. Cancer Res 2014

• Dosing schedule is critical for outcome of combined radio-immunotherapy – concurrently is beneficial

colorectal cancer

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Take home messages

• Numerous trials in progress combining RT + targeted agents • Challenges • Bridge between preclinical and clinical models • Translational research • Biomarkers • Trial design – patient stratification • New toxicities – late effects

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