Basic Clinical Radiobiology 2017

How to measure normal tissue response?

• Scoring of gross tissue effects • Scoring systems: grade the severity of tissue damage using an arbitrary scale • Assays of tissue function • Functional assays to measure radiation effects • E.g. blood counts as an indicator of bone marrow function • Clonogenic assays (L1.4) • Methods by which colony of cells that derive from a single irradiated cell can be observed

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