Brain Tumours

Chordoma Chondrosarcoma

EPIDEMIOLOGY

CHORDOMA

CHONDROSARCOMA

0.84 per 1’000’000 (M>F)* Median age 58 (3 - 95) Intracranial chordomas invariably involve the clivus Those arising from : (a) the most rostral notochordal extension in the dorsum sellae present as sellar/parasellar tumors (b) the most ventral part of the clivus present as nasopharyngeal tumors (c) those associated with body and dorsal aspect of clivus manifest as spheno- occipital or petrosal lesions (d) those related to the lower clivus will present at the ventral portion of the foramen magnum Direct dural invasion responsible for extension to posterior fossa

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5 per 1’000’000 (M>F)

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Median age 51 (1 – 102)

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Appendicular > axial > soft tissue

*Incidence and relative survival of chordomas: the standardized mortality ratio and the impact of chordomas on a population. Smoll NR, Gautschi OP, Radovanovic I, Schaller K, Weber DC . Cancer. 2013 Jun 1;119(11):2029-37. doi: 10.1002/cncr.28032. Epub 2013 Mar 15

03/01/13