Brain Tumours

PHYSIOLOGICAL IMAGING MRI SPECTROSCOPY

NAA : marker of neural integrity Choline : membrane turnover Creatine: energetic Myoinositol : astrocytic marker Lipid : tissue destruction/necrosis marker Lactate: hypoxia marker Glutamine and Glutamate: excitatory markers

High choline correlate with high tumor proliferative index

Pitfalls : - min 1 cm3 voxel size

- not suitable for posterior fossa lesions and lesion - common aspecific spectral findings