Brain Tumours

PHYSIOLOGICAL IMAGING FUNCTIONAL IMAGING - fMRI

• Pitfalls: • Does not monitor the neural response but a “ surrogate ” hemodynamic response • Cannot distinguish essential hubs -> need for intraoperative monitoring • Low localisation accuracy • Neurovascular uncoupling (tumor infiltration zone, neovascularity) with reduced fMRI signal in perilesional cortex • More accurate for motor mapping than for speech • Not giving any functional information about subcortical white matter pathways

Finger Tapping

Semantic speech