Brain Tumours

Dabrafenib Activity in Brain Metastases

• Dabrafenib, at the recommended phase 2 dose, has activity against brain metastases in adult patients with melanoma 1 – Nine of ten (90%) melanoma patients with untreated brain metastases showed reduction in brain lesion size

1. Falchook GS, et al . Lancet 2012;379:1893–1901.

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