CPB Ljubljana 2018 course book

RESULTS OF BRACHYTHERAPY IN KELOIDS

AUTHOR YEAR N.

DOSE RATE

DOSE x FRACTIONS

PRESCRI PTION

TOTAL DOSE

START SESSION

FOLLOW UP (months)

LOCAL CONTROL

LESIONS

Escarmant P et al [68] Arnault JP et al [69] De Cicco L et al [70] Guix B et al [71] Garg MK et al [72]

1993 570

LDR -

5mm 20Gy < 24h

82 months 79%

2009 55

LDR -

5mm 18Gy Within 7h

84 months 76.4%

2014 46 50

LDR HDR

- 4Gy x 3

16 Gy 12 Gy

< 24h

69.6% 62% 96.6% 86.4%

2001 147 periop 22 radical

HDR 5Gy x 4 5Gy x 6 HDR 5Gy x 3

4mm 20Gy 30Gy

Within 1h, 3times a day

84

2004 17

10mm 15Gy < 24h

26

88%

recurrences after RT

Twice a day

Veen RE et al [73]

2007 9

HDR 4Gy + 3Gy x2 6Gy + 4Gy x2 6Gy x 3

10Gy 14Gy 18Gy

Within 6 h

55% 97% 100%

38 7

Arneja JS et al [74] VanLeeuwe n MC et al [75] Jiang P et al [76]

2008 25 ear

HDR 5Gy x 3

3-6mm 15Gy < 24h

36

92%

Twice a day

2014 67

HDR 6Gy x 2

12 Gy Within 4h and 24h

33

96.9%

2016 32

HDR 6Gy x 3

5mm 18 Gy < 24h

29

94%

Twice a day

Hafkamp CJ et al

2017 29

HDR 13Gy x1

13Gy < 24h

53

75.9%

Guinot Jl, Rembielak A, Perez-Calatayud J et al. GEC-ESTRO ACROP recommendations in skin brachytherapy. Radiother Oncol 2018. In press