Course book Advanced Treatment Planning 2018

Parameters for clinical outcome: Brain

30

30

d

< 2.5 Gy

d

≥ 2.5 Gy

n<60 n=160-120 n>120

1

1

25

25

n<60

20

20

n=160-120

n>120

15

15

10

10

5

5

0

0

0 25 50 75 100 125 150 175 200

0 25 50 75 100 125 150 175 200

BED (Gy)

50

Twice daily fraction

45

n<60

40

n=160-120

n>120

35

30

25

Radiation necrosis (%) 20

15

Lawrence YR et al. Radiation Dose-Volume effects in the brain. Int. J. Radiation Oncology Biol. Phys., Vol. 76, No. 3, Supplement, pp. S20–S27, 2010.

10

5

0

0 25 50 75 100 125 150 175 200