ESTRO 2022 - Abstract Book
S750
Abstract book
ESTRO 2022
Figure 1 : Time evolution of the salivation flow by arms Evolution of the salivation flow measured by parafilm stimulation at the inclusion, 6, 12, 18 and 24 months after treatment StnA = Standard Arm RplA = Experimental arm (weekly replanning)
Figure 2 :Evolution of Eisbruch score by arms
Conclusion No significant benefit of ART was found regarding salivary flow and PROM. However, ART allows to improve the excretory function of the parotid gland compared to a standard IMRT, without decreasing local control and overall survival.
OC-0832 DAHANCA 27, a national prospective non-inferiority study of surgery versus RT for T1a glottic cancer
N.M. Lyhne 1 , T. Kjærgaard 2 , C. Godballe 3 , J.F. Tvedskov 4 , K. Hald 5 , B. Ulhøj 6 , T. Printz 7 , J. Overgaard 8
1 Aalborg University Hospital, Department of Otorhinolaryngology, Head and Neck Surgery, Aalborg, Denmark; 2 Aarhus University Hospital, Department of Otorhinolaryngology, Head and Neck Surgery, Århus, Denmark; 3 Odense University Hospital, ORL - Head & Neck Surgery and Audiology, Odense, Denmark; 4 Rigshospitalet, Department of Otorhinolaryngology, Head and Neck Surgery and Audiology, Copenhagen, Denmark; 5 Aalborg University Hospital, Department of Otorhinolaryngology, Head and Neck surgery, Aalborg, Denmark; 6 Århus University Hospital, Department of Pathology, Aarhus, Denmark; 7 University of Southern Denmark, Foniatric institute, Odense, Denmark; 8 Aarhus University Hospital, Department of Experimental Clinical Oncology, Århus, Denmark Purpose or Objective The aim of this study was to evaluate whether treatment with transoral laser microsurgery (TLM) is non-inferior compared to accelerated radiotherapy (RT) in the treatment of T1aN0M0 glottic squamous cell carcinoma (SCC). Materials and Methods Since 2003 the Danish national standard treatment for T1aN0M0 glottic SCC has been accelerated RT (66Gy, 2 GY/fraction, 6 fractions/week). In 2012 cordectomy type I-III using Trans Oral Laser Microsurgery (TLM) was introduced as an
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