ESTRO 2024 - Abstract Book
S1308
Clinical - Head & neck
ESTRO 2024
Figure 2: (A) Example of a tumour increasing in volume (corresponding to dark green line in Figure 1). (B) Example of a tumour decreasing in volume due to resorption of an intralesional haemorrhage (corresponding to pink line in Figure 1).
Conclusion:
During proton beam therapy, uveal melanomas show a minimal change in tumour volume. However, in the weeks leading up to treatment, volume changes larger than 10% were observed in four out of nine patients. Therefore, we advise to keep the time interval between imaging and treatment as brief as possible.
Keywords: uveal melanoma, proton beam therapy, tumour volume
References:
1. Hrbacek J, Mishra KK, Kacperek A, Dendale R, Nauraye C, Auger M, et al. Practice patterns analysis of ocular proton therapy centers: The International Optic Survey. International Journal of Radiation Oncology*Biology*Physics. 2016;95(1):336 – 43. doi:10.1016/j.ijrobp.2016.01.040 2. Fleury E, Trnková P, Erdal E, Hassan M, Stoel B, Jaarma ‐ Coes M, et al. Three ‐ dimensional mri ‐ based treatment planning approach for non ‐ invasive ocular proton therapy. Medical Physics. 2021;48(3):1315 – 26. doi:10.1002/mp.14665 3. Ferreira TA, Jaarsma-Coes MG, Marinkovic M, Verbist B, Verdijk RM, Jager MJ, et al. MR imaging characteristics of uveal melanoma with histopathological validation. Neuroradiology. 2021;64(1):171 – 84. doi:10.1007/s00234-021 02825-5 4. Jaarsma-Coes MG, Klaassen L, Verbist BM, Vu THK, Klaver YLB, Rodrigues MF, et al. Inter-observer variability in MR-based target volume delineation of uveal melanoma. Advances in Radiation Oncology. 2023;8(3):101149. doi:10.1016/j.adro.2022.101149
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