ESTRO 2024 - Abstract Book

S1324

Clinical - Head & neck

ESTRO 2024

Keywords: Xerostomia, Diffusion Weighted Imaging

1687

Digital Poster

Global dose prescription variances in oropharynx cancer

Christian Rønn Hansen 1,2,3 , Tony Tadic 4 , Andrea McNiven 4 , Jens Petersen 5,6 , Sharma Manju 7 , Gareth Price 8 , Mohamed A. Naser 9,10,11 , Pernille Lassen 12 , Jens Overgaard 12 , Lachlan McDowell 13 , Jun Won Kim 14 , Clifton David Fuller 9,10,11 , David Thomson 8 , Sue S. Yom 7 , Jørgen Johansen 15 , Jeppe Friborg 5 , Andrew Hope 16 1 Laboratory of Radiation Physics, Odense University Hospital, Odense, Denmark. 2 Institute of Clinical Research, University of Southern Denmark, Odense, Denmark. 3 Danish Center of Particle Therapy, Aarhus University Hospital, Aarhus, Denmark. 4 Department of Medical Physics, Princess Margaret Cancer Centre, Toronto, Canada. 5 Department of Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark. 6 Department of Computer Science, University of Copenhagen, Copenhagen, Denmark. 7 Department of Radiation Oncology, University of California San Francisco, San Francisco, USA. 8 Division of Cancer Sciences, University of Manchester, The Christie NHS Foundation Trust, Manchester, United Kingdom. 9 Department of Radiation Oncology, Baylor College of Medicine, Houston, USA. 10 Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, USA. 11 Medical Physics Program, The University of Texas Graduate School of Biomedical Sciences, Houston, USA. 12 Department of Experimental Clinical Oncology, Aarhus University Hospital, Aarhus, Denmark. 13 Department of Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia. 14 Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of. 15 Department of Oncology, Odense University Hospital, Odense, Denmark. 16 Department of Otolaryngology-Head Neck Surgery, Princess Margaret Cancer Centre, Toronto, Canada

Purpose/Objective:

Radiotherapy treatment planning hinges on a critical factor: the prescribed dose. Surprisingly, no consistent, standardised global approach to interpreting this prescription exists. This study aimed to examine and illustrate the variations in prescribed doses for the same treatment across North European, North American, and Asian centres. The objective was to gain insights into the dosimetric variations for oropharynx cancer treatment.

Material/Methods:

The study analysed consecutively treated oropharynx cancer patients from seven globally recognised radiotherapy departments. The inclusion criteria encompassed curative intensity-modulated radiation therapy (IMRT) or volumetric modulated arc therapy (VMAT) administered in 2017 or later. These centres were categorised into three North American, three North European centres, and one Asian centre.