ESTRO 2024 - Abstract Book

S1551

Clinical - Lower GI

ESTRO 2024

established method to move the ovaries away from the irradiation field, similar surgical procedures regarding the uterus remain investigational. The aim of this study was to carry out a systematic review of the literature on uterine displacement techniques (ventrofixation/ transposition) and to simulate the radiation dose received by the uterus in different heights place after the procedures.

Material/Methods:

The systematic review was performed according PRISMA guidelines. PubMed, Scopus, Web of Science and EMBASE were queried to identify included study until March 2023. Retrospectively, a dosimetric study was also performed to assess the dose received by the uterus according to hypothetical different displacement positions taking the case of irradiation for rectal or anal cancer as model.

Results:

A total of 187 studies were included, after the screening 9 studies were selected for synthesis. Data from the dose simulation revealed that the transposition approach was the most protective with a maximum dose of about 3 and 8 Gy for anal and rectal cancer respectively. None of the simulated ventrofixation positions received a Dmean surpassing 14 Gy.

Conclusion:

According to the literature review and the simulation results of the present study we may conclude that simple elevation of the uterus by ventrofixation of the fundus should be further evaluated as a fertility sparing approach in young rectal/anal cancer patients

Keywords: Fertility sparing, uterine transposition

2780

Digital Poster

Adjuvant radiotherapy after local excision instead of radical surgery for early-stage rectal cancer.

Sofia Santana Jimenez 1 , Jesus Romero Fernandez 1 , Arsenio Sanchez Movilla 2 , Sofia Cordoba Largo 1 , Raquel Benlloch Rodriguez 1 , Isabel Alonso Sebastian 2 , Alberto Herreros de Tejada Echanojauregui 3 , Marta Lopez Valcarcel 1 , Maria Hernandez Miguel 1 , Beatriz Gil Haro 1 , Irma Zapata Paz 1 , Sara Perez Mata 1 , Francisco Javier Martinez Paredes 1 , Jose Santiago Garcia 3 1 Puerta de Hierro University Hospital, Radiation Oncology, Madrid, Spain. 2 Puerta de Hierro University Hospital, Surgery, Madrid, Spain. 3 Puerta de Hierro University Hospital, Gastroenterology, Madrid, Spain

Purpose/Objective:

Surgery is the main and curative treatment in rectal cancer.