ESTRO 2024 - Abstract Book
S1824
Clinical - Lung
ESTRO 2024
This research sought to present preliminary findings from the use of single-dose stereotactic radiotherapy (RT) in treating patients with inoperable lung tumors.
Material/Methods:
At our center, patients received treatment using single-dose SBRT (25 Gy and 30 Gy , 80% isodose). The study encompassed patients with inoperable T1-2N0 non-small cell lung cancer (NSCLC) or isolated lung metastases. The SBRT was administered during a gated breath-hold with a planning target volume (PTV) margin set between 3-5 mm. Real-time CBCT scans were evaluated to assess the accuracy and efficacy of the gated delivery method.
Results:
The study involved 95 patients presenting 120 lesions (comprising 61 NSCLC and 59 metastatic tumors). Among the entire cohort, 23 out of 120 lesions experienced local failure. Local control rates over 12, 24, and 36 months were 88%, 82%, and 75%, respectively. Within the NSCLC group, 9 out of 61 lesions showed in-field failures, with local control rates at 12, 24, and 36 months being 94%, 85%, and 80%. Meanwhile, for the group with pulmonary metastases, 14 out of 59 lesions experienced local failure, and the control rates over 12, 24, and 36 months were 80%, 75%, and 65%, respectively. Only 6 out of 95 patients exhibited Grade II pneumonitis. No patient displayed Grade 3 or 4 toxicities.
Made with FlippingBook - Online Brochure Maker