ESTRO 2024 - Abstract Book

S1969

Clinical - Mixed sites, palliation

ESTRO 2024

MRgRT and SMART represents a novel approach in Spain, with the ability to adapt OARs, leading to improved clinical outcomes and reduced toxicity. The implementation of these techniques has been successful, with acute toxicity rates consistent with the literature, and we have demonstrated feasibility in daily adaptation and quality assurance after 4 months of implementation. We eagerly await our late toxicity results.

Keywords: SMART, MRgRt, toxicity

References:

1-. Kishan AU, Ma TM, Lamb JM, Casado M, Wilhalme H, Low DA, Sheng K, Sharma S, Nickols NG, Pham J, Yang Y, Gao Y, Neylon J, Basehart V, Cao M, Steinberg ML. Magnetic Resonance Imaging-Guided vs Computed Tomography Guided Stereotactic Body Radiotherapy for Prostate Cancer: The MIRAGE Randomized Clinical Trial. JAMA Oncol. 2023 Mar 1;9(3):365-373. doi: 10.1001/jamaoncol.2022.6558. PMID: 36633877; PMCID: PMC9857817.

2-. Hunt A, Hansen VN, Oelfke U, Nill S, Hafeez S. Adaptive Radiotherapy Enabled by MRI Guidance. Clin Oncol (R Coll Radiol). 2018 Nov;30(11):711-719. doi: 10.1016/j.clon.2018.08.001. Epub 2018 Sep 7. PMID: 30201276.

3-. Bryant JM, Weygand J, Keit E, Cruz-Chamorro R, Sandoval ML, Oraiqat IM, Andreozzi J, Redler G, Latifi K, Feygelman V, Rosenberg SA. Stereotactic Magnetic Resonance-Guided Adaptive and Non-Adaptive Radiotherapy on Combination MR-Linear Accelerators: Current Practice and Future Directions. Cancers (Basel). 2023 Mar 30;15(7):2081. doi: 10.3390/cancers15072081. PMID: 37046741; PMCID: PMC10093051

2313

Digital Poster

Changes in local bone density after pelvic radiotherapy in patients with pelvic malignancies

NEERAJ KUMAR RATHEE 1 , NIDHI - GUPTA 1 , salman khurshid shah 2

1 GMCH Chandigarh, RADIATION ONCOLOGY, CHANDIGARH, India. 2 Vydehi institute of medical sciences, Radiation oncology, Bangalore, India

Purpose/Objective:

Osteoporosis is characterized by decrease in bone density or bone mass along with deterioration in architectural design of bone tissue leading to fragility in bone. Mostly pelvic insufficiency fracture as a result of decrease in bone density is a complication following pelvic radiotherapy are commonly seen within first 12 months of radiotherapy completion. The objective of this study was to find out the change in local bone density when radiation is delivered to the pelvic region

Material/Methods:

This prospective Cohort study conducted in the Department of Radiation Oncology at Government Medical College and Hospital, Chandigarh.included prospective data of 50 patients of either sex ,age >18 years undergoing pelvic