ESTRO 2024 - Abstract Book

S1970

Clinical - Mixed sites, palliation

ESTRO 2024

radiotherapy.Baseline investigations: - blood investigations (serum calcium, serum phosphorus and serum alkaline phosphate), NCCT pelvis and DEXA scan. BMD was automatically calibrated to internal reference of muscle and subcutaneous fat. T score and Z score were calculated by using DEXA Scan. Average BMD, T score and Z score were noted before the start of radiotherapy and 3 months post radiotherapy follow up.

Results:

We have found that there were change in mean serum calcium, phosphorous and ALP levels from start of pelvic RT and 3 months follow up (8.31 + 0.54, 9.99 + 10.55), (2.82 + 0.32, 2.85 + 0.284) and (107.93 + 35.63, 109.60 + 31.96) however, the changes were not statistically significant with p value (0.264, 0.075 and 0.365) respectively. We also found that there was change in bone mineral density and T score before and after pelvic RT (0.54 + 0.20, 0.53 + 0.22) and (-1.08 + 0.57, -1.09 + 0.58) and the change was not statistically significant p value (0.164 and 0.322) respectively. There was no change in Z score.

Conclusion:

There was change in serum calcium, phosphorous and alkaline phosphatase. level from start of pelvic radiotherapy to 3 months follow up. There was also change in bone mineral density and T score before and 3 months of follow up.

Keywords: pelvic malignancy , bone density, late toxicity

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Efficacy and safety evaluation of radiotherapy for Periarthitis of the shoulder (PHS).

Tomasz Latusek 1 , Grzegorz Wozniak 1 , Donata Graupner 2 , Aleksandra Krzywon 3 , Alexander Jorge Cortez 3 , Dorota Gabrys 1 1 Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Radiotherapy Department, Gliwice, Poland. 2 Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, III Department of Radiotherapy and Chemotherapy, Gliwice, Poland. 3 Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, Department of Biostatistics and Bioinformatics, Gliwice, Poland

Purpose/Objective:

Periarthritis of the shoulder (“painful shoulder syndrome”) is a hurtful degenerative skeletal disorder of the shoulder joint and the surrounding tendons. PHS embraces many disorders of the shoulder joint, which affects patients’ quality of life due to pain and mobility problems. The etiology and pathogenesis of this disease are still not well known. Among a large variety of treatment options, radiotherapy (RT) represents a relevant method. The aim of the study was to evaluate the efficacy and safety of RT in the treatment of PHS.