ESTRO 2024 - Abstract Book

S1981

Clinical - Mixed sites, palliation

ESTRO 2024

2667

Digital Poster

Clinic-wide PROMs of all radiotherapy patients: a pilot study

P Munck af Rosenschold 1,2 , M P Nilsson 3,4 , I Kristensen 2 , V Rogowski 1,2 , E Wieslander 2 , M Jansson 2 , S Said 2 , K Jonsson 2 , M Kadhim 2 , K Svedberg 2 , M Jerkeman 3 1 Lund University, Medical Radiation Physics, Lund, Sweden. 2 Skåne University Hospital, Radiation physics, Department of Hematology, Oncology and Radiation Physics, Lund, Sweden. 3 Skåne University Hospital, Oncology, Department of Hematology, Oncology and Radiation Physics, Lund, Sweden. 4 Lund University, Oncology, Lund, Sweden

Purpose/Objective:

*Nilsson / Munck are co-first authors.

The purpose of the current study was to assess the feasibility of a clinic-wide Patient-reported outcome measures (PROMs) program for patients to a single institution radiotherapy department. Our initial aim was to exceed 50% enrollment during the first year. With general application of a PROMs program, we aim to (1) investigate trends within the patient cohort, (2) establish side-effects based dose-response models for large number of patients, and (3) improve the understanding of the quality-of-life (QoL) impact for our patients. Our PROMs program may allow for quantification of departmental procedures improvements, such by introduction of new treatment technology or altered treatment protocols.

Material/Methods:

Data were extracted from an ongoing project that was initiated 31st of January 2022, and data was extracted from start to the 31st of September 2023. The inclusion criteria were limited to 18 years and older, able to follow and respond to instructions, able to speak and understand Swedish, and independently able to use a smartphone. The patients were asked to fill in the EORTC QLQ C30 report prior to each course of radiotherapy and subsequently yearly thereafter. Enrollment was performed at the first visit at the radiotherapy department, which was generally at the treatment planning CT. Functioning and Symptoms scales were calculated from PROMs data. The data was split into 70% training and 30% testing sets and neural networks were utilized to predict any (yes/no) deterioration in Global Health (GH), Physical Functioning (PF), Role Functioning (RF), Emotional Functioning (EF), Cognitive Functioning (CF) and Social Functioning (SF) scales from PROMs data prior to radiotherapy.

Results:

A total of 8116 patients were eligible for enrollment during the study period, of which 2526 (31%) met inclusion criteria and initially agreed to share data. However, 377 patients did not proceed with submitting the report, and thus 2149 patients were evaluable (27%), and of which 692 patients (8.5%) had submitted multiple questionnaires. The patients had a median age of 67 (21-92) years, 1214 female and 935 patients were male, the staff-assessed median performance status prior to radiotherapy was 0 (range: 0-3, n=700). Common symptoms prior to