ESTRO 2024 - Abstract Book

S196

Brachytherapy - GI, paediatric, miscellaneous

ESTRO 2024

37 patients continue to be on observation Fig 1. Hence organ preservation rate achieved in 37( 62.7%0. of the patients. Of the 22 patients undergoing surgery complete pathological response was seen in 5 (22.5%) of the patients. Sphincter-preserving surgeries were done in 15(68%) of the patients.

The primary T stage affected the outcomes. The majority 12 of the 13 (92%) T2 tumors achieved cCR whereas 28 of the 46 (60.8%) patients had cCR/nCR p_0,04

Till now Grade 2 late rectal toxicity has been observed in 3 patients and grade 3 in 2 patients

Updated results will be presented in the meeting

Conclusion:

Dose Escalated Radiotherapy using MRI guided Ir 192 –brachytherapy leads to better complete and near complete clinicoradiological thus improving the rate of organ preservation for distal rectal cancers

Keywords: Rectal brachytherapy, Organ preservation

References:

1. Appelt AL, Pløen J, Harling H, Jensen FS, Jensen LH, Jørgensen JCR, et al. High-dose chemoradiotherapy and watchful waiting for distal rectal cancer : a prospective observational study. :919–27.

2. Sun Myint A, Smith FML, Gollins S, Wong H, Rao C, Whitmarsh K, et al. Dose Escalation Using Contact X-ray Brachytherapy After External Beam Radiotherapy as Nonsurgical Treatment Option for Rectal Cancer: Outcomes From a Single-Center Experience. Int J Radiat Oncol Biol Phys [Internet]. 2018;100(3):565–73. Available from: https://doi.org/10.1016/j.ijrobp.2017.10.022