ESTRO 2024 - Abstract Book

S2882

Interdiscplinary - Other

ESTRO 2024

Figure 1 - ROS enhancement factor across time obtained for the three sources simulated: protons (squares), X rays (triangle) and Co-60 (circles).

Figure 2 - Radial dose enhancement factor obtained for the three irradiation qualities simulated.

Conclusion:

In vitro studies have consistently demonstrated that the combination of AuNPs with ɣ -rays yields no significant radiosensitizing impact [4,5]. Our own results substantiate this observation, as we find no noticeable additional physical or chemical effects. Conversely, when low-energy X-rays and protons are combined with AuNPs, a notable enhancement in radiation effectiveness has been described [5]. Our data suggest that, when AuNPs are combined with low-energy X-rays, the primary influential mechanism is of a physical nature. This is evident because, while