ESTRO 2024 - Abstract Book

S3882

Physics - Image acquisition and processing

ESTRO 2024

This study proposes an informed construction of the CTV by incorporating musculoskeletal information, redirecting the radiation target volume away from potentially uninvolved tissues. Future studies will focus on the anatomical validation of the cadaveric approach.

Keywords: Target volume definition, cadaver, sarcoma

References:

[1] Beunk, Brown, K., Nagtegaal, I., Friedl, P., & Wolf, K. (2019). Cancer invasion into musculature: Mechanics, molecules and implications. Seminars in Cell & Developmental Biology, 93, 36–45. https://doi.org/10.1016/j.semcdb.2018.07.014

[2] Ackerman, M. J. (1998). The visible human project. Proceedings of the IEEE, 86(3), 504-511.

[3] Shusharina, N., Liu, X., Coll-Font, J., Foster, A., El Fakhri, G., Woo, J., ... & Nguyen, C. (2022). Feasibility study of clinical target volume definition for soft-tissue sarcoma using muscle fiber orientations derived from diffusion tensor imaging. Physics in Medicine & Biology, 67(15), 155013.