ESTRO 2024 - Abstract Book

S4076

Physics - Inter-fraction motion management and offline adaptive radiotherapy

ESTRO 2024

Maximum Dose (Gy)

Minimum Dose (Gy)

Mean Dose (Gy)

Structure

Dose Summation Volume (cc)

DCS

DIR

97.32±29.0

0.47±0.2

32.20±18.7

2.25±1.8

10.39±8.5

Duodenum

Physical Sum

39.05±29.1

1.38±1.1

8.95±5.8

Esophagus

DIR

16.60±6.6

0.70±0.1

16.00±7.5

2.76±2.1

8.17±4.1

Physical Sum

28.30±20.2

1.97±0.9

11.00±7.6

DIR

631.00±103.0

0.89±0.1

28.92±20.5

1.55±0.8

6.24±3.9

Heart

Physical Sum

39.30±29.0

1.21±0.8

6.62±4.3

DIR

952.80±620.9

0.38±0.2

39.69±16.9

1.19±0.7

7.63±3.7

Large Bowel

Physical Sum

45.63±25.7

1.04±0.8

7.63±4.8

DIR

1610.57±453.6

0.91±0.1

82.6±62.7

1.36±0.9

14.28±8.7

Liver

Physical Sum

118.50±58.3

1.10±0.9

21.11±17.6

DIR

172.50±57.2

0.93±0.1

18.24±15.1

1.80±1.3

5.55±3.9

Lt Kidney

Physical Sum

19.32±15.5

1.27±1.1

5.46±4.5

DIR

163.50±45.5

0.92±0.1

34.93±23.4

1.55±0.8

7.47±4.9

Rt Kidney

Physical Sum

34.92±27.4

1.39±1.5

7.13±5.8

DIR

173.20±88.1

0.20±0.05

16.83±9.6

1.49±0.9

4.77±1.9

Small Bowel

Physical Sum

29.01±28.6

1.03±1.0

4.53±3.4

DIR

26.66±14.8

0.59±0.2

18.02±6.6

1.31±0.7

6.87±3.1

Spinal Cord

Physical Sum

28.21±12.5

1.53±0.8

8.65±4.2

DIR

332.68±174.8

0.68±0.1

38.27±17.6

1.41±0.9

7.96±2.9

Stomach

Physical Sum

38.45±14.4

1.34±1.2

6.75±3.8

Table 1:Dosimetric details using Physical dose summation and Deformable registration based summation for various OARs.

Table 1 shows the detailed findings of each OAR quality assessment using DIR. When compared to physical dose summation, DIR-based dose accumulation demonstrated significant variations with high variability in patients and OARs. Figure 1 illustrates a qualitative depiction of a patient who received four treatments and the cumulative dose distribution using DIR.