ESTRO 2024 - Abstract Book

S4207

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2024

To summarize, the biggest challenge the PGT method is facing now is the very limited of useful events. To overcome this, alternative data acquisition systems allowing higher throughputs are being tested as well as different approaches for combining signals from multiple detectors. Moreover, a future clinical application of PGT requires the development of more sophisticated methods (including AI) for modeling and predicting proton range deviations in complex targets and more efficient detector systems.

Keywords: prompt gamma-ray timing, proton range verification

References:

[1] Golnik, Christian et al. (Sept. 2014). “Range assessment in particle therapy based on prompt γ -ray timing measurements”. In: Physics in Medicine and Biology 59 (18), pp. 5399–5422. issn: 0031-9155. doi: 10.1088/0031 9155/59/18/5399. [2] Werner, Theresa et al. (May 2019). “Processing of prompt gamma-ray timing data for proton range measurements at a clinical beam delivery”. In: Physics in Medicine and Biology 64 (10), p. 105023. issn: 0031-9155. doi: 10.1088/1361 6560/ab176d. url: https://iopscience.iop.org/article/10.1088/1361-6560/ab176d. [3] Marcatili, S et al. (Dec. 2020). “Ultra-fast prompt gamma detection in single proton counting regime for range monitoring in particle therapy”. In: Physics in Medicine and Biology 65 (24), p. 245033. issn: 0031-9155. doi: 10.1088/1361-6560/ab7a6c. url: https://iopscience.iop.org/article/10.1088/1361-6560/ab7a6c. [4] Schellhammer, Sonja M. et al. (Aug. 2022). “Multivariate statistical modelling to improve particle treatment verification: Implications for prompt gamma-ray timing”. In: Frontiers in Physics 10. issn: 2296-424X. doi: 10.3389/fphy.2022. 932950.

927

Mini-Oral

Patient-specific deep learning for real-time tumor tracking in MR-guided radiotherapy

Laura Velezmoro 1 , Elia Lombardo 1 , Sebastian Marschner 1 , Michael Reiner 1 , Stefanie Corradini 1 , Claus Belka 1,2,3 , Marco Riboldi 4 , Christopher Kurz 1 , Guillaume Landry 1 1 LMU University Hospital, Department of Radiation Oncology, Munich, Germany. 2 German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and LMU University Hospital, Munich, Germany. 3 Bavarian Cancer Research Center, (BZKF), Munich, Germany. 4 Faculty of Physics, Ludwig-Maximilians-Universität München, Department of Medical Physics, Garching, Germany

Purpose/Objective: