ESTRO 2024 - Abstract Book

S5013

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2024

at least X Gy) was found to be the most significant predictor of G3+RIL up to 1 week post-RT (lowest AIC, p <0.05). In contrast, in the 4-8 and 8-12 weeks post-RT, none of lungs and body DVH parameters were found to be a significant predictor, whereas thoracic vertebral body dosimetric factors, especially V20 and V30, demonstrated significant effect. In multivariate analyses presented in Table 1, baseline ALC was consistently selected as a significant factor throughout all evaluated periods. Up to 1 week post-RT, thoracic vertebral body V5 [%] remained significant, whereas thoracic vertebral body V30 [%] and V20 [%] remained in 4-8 and 8-12 weeks after RT respectively. None of the dosimetric factors, except baseline ALC and prescribed dose, was found to be significant factors in 1-4 weeks after RT.