ESTRO 2024 - Abstract Book

S5124

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2024

Each prostate was contoured in the Raystation treatment planning system (5) on the T2w FSE image. To correct for motion, each dynamic image of the dynamic sequence was rigidly registered to the T2-weighted image in an in-house image-registration software to enable the use of the prostate contours on dynamic images. Median signal intensity for the complete prostate was extracted from each registered dynamic image, normalised and plotted against timepoint. In order to determine if there was a significant change in signal due to the switch to 100% oxygen, the signal on air at timepoints 3-20 and on oxygen breathing timepoints 46-60 were compared by an unpaired t-test, with a significance level of p < 0.05 required to indicate a significant signal change.

Results:

Figure 1 shows the whole prostate median signal time series for each patient visit.

Table 1 shows the percentage signal intensity change for each patient between breathing air and breathing 100% oxygen and the corresponding p-value from the t-test.