ESTRO 2024 - Abstract Book

S581

Clinical - Breast

ESTRO 2024

From 65 participants have completed one of the 3 protocols with average age of 57.8 years old, 30 (46.1%) had left site disease, 35 (53.9%) had right site disease and 50 (77%) underwent sentinel lymph node biopsy (SNLN), 5 (7.7%) underwent axillary lymph node dissection (ALND) as part of their treatment. 14 (21.5%) women had lymphedema at baseline, 10 (71.5%) in SNLN group and 4 (28.5%) in ALND group. There were no participants with had any worsening lymphedema after completing the exercise regimen. For all 65 participants (highlighted in table 1), lean mass right arm, lean mass left arm had significantly positive change comparing to before exercise training (all p < .05). Also, the edema index (ECW/TBW, ECW/TBW right arm, ECW/TBW left arm) did show significant improvement after exercise for all patients (all p <.05). The improvement in edema index after exercise stayed consistent for SNLN group (highlighted in table 2) but did not show significant change for ALND group (highlighted in table 3).

Table 1. InBody comparison for all patients

Variable

InBody at baseline

Inbody after exercise P value

Lean mass right arm 5.49(1.04)

5.57(1.01) 5.47(0.98) 4.34(0.79) 4.26(0.76) 2.69(0.48) 2.64(0.47) 1.65(0.31) 1.62(0.29)

.0033 .0008 .0043 .0008 .0011 .0002 .0406 .0105 .0423

Lean mass left arm

5.39(1.04) 4.28(0.81) 4.20(0.81) 2.65(0.50) 2.60(0.50) 1.63(0.32) 1.60(0.31)

TBW right arm TBW left arm ICW right arm

ICW left arm

ECW right arm

ECW left arm

ECW/TBW

0.386(0.006) 0.381(0.004) 0.381(0.004)

0.385(0.006) 0.380(0.005) 0.380(0.004)

ECW/TBW right arm

<.0001 <.0001

ECW/TBW left arm

Table 2. InBody comparison for SNLN group

Variable

InBody at baseline

InBody after exercise P value

Lean mass right arm 5.57(0.97)

5.64(0.93) 5.54(0.93) 4.39(0.73) 4.32(0.72) 2.72(0.45) 2.68(0.44) 1.67(0.28) 1.64(0.28)

.0121 .0022 .0140 .0022 .0068 .0007 .0850 .0231 .0236 .0002

Lean mass left arm

5.56(0.99) 4.34(0.76) 4.25(0.78) 2.69(0.46) 2.63(0.48) 1.65(0.30) 1.62(0.30)

TBW right arm TBW left arm ICW right arm

ICW left arm

ECW right arm

ECW left arm

ECW/TBW

0.385(0.005) 0.381(0.004) 0.381(0.004)

0.384(0.004) 0.379(0.004) 0.380(0.003)

ECW/TBW right arm ECW/TBW left arm

<.0001

Table 3. InBody comparison for ALND group