ESTRO 2024 - Abstract Book

S639

Clinical - Breast

ESTRO 2024

Conclusion:

For the first time in these endpoints, the considered Organ at Risk for the dosimetry was the first 5 mm of the breast skin. The volume receiving 20 Gy, 50% of the prescription dose, was applied as a dosimetric descriptor in the model and was able to replace the PTV model, giving, at the same time, the possibility to better interpret the damage in terms of irradiated skin as well as being more independent on the contouring phase. In addition, V42 Gy was entered into the model to describe the cooperation between serial and parallel characteristics of the skin tissue for such symptoms. While hormonal therapy with aromatase inhibitors was a protective factor, a poor cosmetic status after surgery heavily increased the risk of FATP.

Keywords: late fibrosis, NTCP model, skin dose

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