ESTRO 2024 - Abstract Book

S771

Clinical - CNS

ESTRO 2024

Conclusion:

This study represents the first evaluation of the human connectome before and after WBRT. Analysis of the human connectome can reveal significant changes in functional networks, parcellations, nodes, and hubs that are not appreciated by standard follow-up MRI and correlate with neurocognitive testing. Further studies in a larger cohort are underway and correlations with neurocognitive outcomes, white matter changes, and tumor locations/numbers will be performed.

Keywords: WBRT, Neurocognitive outcomes, Connectomics