ESTRO 2025 - Abstract Book

S1127

Clinical – Head & neck

ESTRO 2025

Purpose/Objective: Bucco-facial nodes are at risk of harboring metastases from cancers of the skin of the face, the nose, the maxillary sinus, and the buccal mucosa. The incidence of level IX involvement is unknown, likely below 10%. This multicentric study aims to elucidate the incidence of metastases to level IX nodes. Material/Methods: A search for eligible patients was conducted using the Aria, Mosaiq, and Redcap databases. Inclusion criteria were patients with a first diagnosis or recurrent neoplasm involving the cheek mucosa, retromolar trigone, oral gum, nasal cavity, nasal vestibule, and paranasal sinuses. Results: We reviewed the records (CT, MRI, PET) of 83 patients. The subsite distribution was as follows: 23 nasal vestibule, 18 retromolar trigone, 17 cheek mucosa, 12 nasal cavity, 6 maxillary sinus, 2 ethmoid sinus, and 5 oral gum. Level IX positivity was identified in 6 out of 83 patients (7%). Of these, 3 were detected via clinical imaging as loco-regional recurrences (2 in the retromolar trigone, stage pT3 pN3b, and pT4 pN3b and 1 in the cheek mucosa pT3 pN2b), and 1 as locally advanced involging retromolar trigone region cT4b cN3b. Two cases were identified through histopathological reports in patients without preoperative imaging evidence (1 retromolar trigone, pT4a pN1, and 1 cheek mucosa, pT2 pN2b). Two of the four patients died from rapidly progressive disease. Conclusion: The incidence of buccofacial node involvement was rare. However, the risk of nodal metastasis in level IX was higher (22 %) for tumors involving the retromolar trigone and 12 % for cheek mucosa. These findings may reflect both the advanced stage of the disease and its specific subsite. Therefore, prophylactic irradiation of level IX in these subsites should be recommended. Digital Poster Psychological Impact of Radiodermatitis After Radiotherapy for Head and Neck Cancer: A 5-Year Retrospective Study amina majdi 1,2 , fatima zahra chraa 1,2 , Chadia Ezzouitina 1,2 , rachida laraichi 1 , Hajiba Moubarik 1,2 , Amine Lachgar 1,2 , karima nouni 1,2 , hanan el kacemi el kacemi 1,2 , Tayeb kebdani 1,2 , Khalid hassouni 1,2 1 Radiotherapy, National Institute of Oncology, Rabat, Morocco. 2 Faculty of medicine and pharmacy, Medicine, Rabat, Morocco Purpose/Objective: Radiodermatitis is a frequent and debilitating complication of radiotherapy (RTH) for head and neck cancers, with consequences extending beyond physical discomfort to include significant psychological distress. This study evaluates its psychological impact, focusing on depression, anxiety, quality of life, and related predictors over five years. Material/Methods: A retrospective study was conducted at the National Oncology Institute in Rabat, examining patients treated with radiotherapy for head and neck cancers between January 2019 and December 2023. Data included: • Psychological assessments: Anxiety (HAM-A), depression (BDI), self-esteem (Rosenberg Self-Esteem Scale), and quality of life (SF-36 Health-Related Quality of Life questionnaire). • Clinical evaluations: Radiodermatitis severity grading. Keywords: Oral cavity cancer, IX level, Nasal cancer 4331