ESTRO 2025 - Abstract Book

S1128

Clinical – Head & neck

ESTRO 2025

Results: Prevalence of Radiodermatitis Out of 300 patients, 70% (n = 210) developed radiodermatitis: • 45% (n = 135): Grade 2 severity. • 25% (n = 75): Grade 3 severity. Psychological Impact Depression: • 65% (n = 137) of patients with Grades 2–3 radiodermatitis experienced depressive symptoms, compared to 20% (n = 18) with mild or no radiodermatitis. • Mean depression scores: 13.5 ± 3.4 (severe cases) versus 6.8 ± 2.5 (mild/no cases). Anxiety: • 60% (n = 126) of patients with Grades 2–3 radiodermatitis reported elevated anxiety levels, compared to 28% (n = 25) in the mild/no group. • Mean anxiety scores: 12.8 ± 3.2 (severe cases) versus 7.4 ± 2.7 (mild/no cases). Quality of Life Patients with severe radiodermatitis scored 54 ± 11 on the SF-36 scale, compared to 73 ± 9 for mild or no radiodermatitis. • Social functioning: Patients reported difficulties in maintaining relationships due to visible skin changes. • Emotional well-being: Persistent distress resulted from altered appearance and discomfort. Predictors of Psychological Distress Key factors included: • Severity: Grade 3 cases were 3.5 times more likely to experience severe symptoms. • Gender: Women reported higher distress (72% vs. 50% in men). • Age: Younger patients (<50 years) exhibited higher anxiety and depression. • Social support: Limited networks were linked to lower self-esteem and poorer quality of life. Access to Psychosocial Support Of all patients, 35% (n = 105) sought psychological counseling. Among them, 70% reported improved coping mechanisms and emotional well-being, emphasizing the need for integrated psychosocial care. Conclusion: Radiodermatitis has profound psychological consequences, significantly impacting the quality of life in head and neck cancer patients. Incorporating psychosocial support within oncology care is crucial for mitigating distress and improving overall outcomes.

Keywords: Radiodermatitis, radiotherapy, psychology

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Digital Poster Prognostic capacity of pretreatment hematological parameters in patients with Head and neck cancer treated with chemo-bio Radiotherapy Laura C Monetzuma 1 , Scarlet Crespo 1 , Xavier Leon 2 , Katarina Majercakova 1 , Jady V Rojas 1 , Magui Piedra 1 , Gemma Calvet 1 , Saba Rabi 1 , Joan C Julia 1 , Gemma Sancho 1 1 Radiation Oncology, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain. 2 Otorhinolaryngology Department, Hospital de la Santa Creu I Sant Pau, Barcelona, Spain Purpose/Objective: Hematological parameters obtained from a blood test before treatment, and indices as the “host index” (HI) that are calculated from these parameters, are related to the prognosis of the disease in patients with squamous cell carcinomas of the head and neck (1,2). The objective is to determine which of the hematological parameters have