ESTRO 2025 - Abstract Book

S2332

Interdisciplinary – Health economics & health services research

ESTRO 2025

Conclusion: The review highlights the paucity and large heterogeneity of PT costing data available in the literature. These findings underscore the need for a standardized costing framework for PT, ensuring consistent methodology, definitions and outputs, in order to facilitate data-driven economic evaluations and inform reimbursement decisions.

Keywords: Costing, Particle-Therapy, Economic-Evaluation

References: (1). Lievens Y, Nagels K. Economic data for particle therapy: Dealing with different needs in a heterogeneous landscape. Radiotherapy and Oncology. 2018 Jul 1;128(1):19-25. (2). Mandrik OL, Severens JH, Bardach A, Ghabri S, Hamel C, Mathes T, Vale L, Wisløff T, Goldhaber-Fiebert JD. Critical appraisal of systematic reviews with costs and cost-effectiveness outcomes: an ISPOR good practices task force report. Value in Health. 2021 Apr 1;24(4):463-72. (3). Husereau D, Drummond M, Petrou S, Carswell C, Moher D, Greenberg D, Augustovski F, Briggs AH, Mauskopf J, Loder E. Consolidated health economic evaluation reporting standards (CHEERS) statement. Bmj. 2013 Mar 25;346.

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Digital Poster The Irish Research Radiation Oncology Group (IRROG). Setting up a national research radiation oncology group, the Irish experience to date. Sinead Brennan 1,2,3 , Roisin O Maolalai 2 , Emma Noone 4 , Valerie Owens 5 , Joseph Martin 6 , John Armstrong 1 , Aisling Barry 7 , Paul J Kelly 8 , Rebecca O'Donovan 4 , Sarah Murphy 4 , Vitor Oliveira 4 , Jackie McCann 4 , Margaret Looby 4 , Bahareh Khosravi 4 , Emma Stone 9 , Laura Nally 9 , Ella O'Sullivan 10 , Karen Molan 11 , Roisin Conaty 12 , Vijayashree Hegde 4 , Neerej Satish 4 1 Radiation Oncology, SLRON, Dublin, Ireland. 2 Research, Irish Research Radiation Oncology Group, Dublin, Ireland. 3 Applied Radiation Therapy Trinity, Discipline of Radiation Therapy, Trinity St.James’s Cancer Institute, Trinity College Dublin, Dublin, Ireland. 4 Clinical Trials Unit, SLRON, Dublin, Ireland. 5 Research, St. Luke's Institute of Cancer Research, Dublin, Ireland. 6 Radiation Oncology, University Hospital Galway, Galway, Ireland. 7 Radiation Oncology, Cork University Hospital, Cork, Ireland. 8 Radiation Oncology, Bon Secours UPMC, Cork, Ireland. 9 Clinical Trials Unit, University Hospital Galway, Galway, Ireland. 10 Clinical Trials Unit, Cork University Hospital, Cork, Ireland. 11 Clinical Trials Unit, Bon Secours UPMC, Cork, Ireland. 12 Clinical Trials Unit, Beacon Hospital, Dublin, Ireland Purpose/Objective: Equitable access to clinical trials cannot exist in a setting where clinical trials are restricted to a limited, centralised number of radiotherapy institutions (1,2). Established in January 2022, IRROG unifies the five Irish public radiotherapy departments and three private departments and is supported by a National Health Research Board infrastructure grant. IRROG’s mission is to improve collaboration between radiation oncology researchers and develop infrastructure to increase the number of high-quality interventional trials nationally, thereby rapidly increasing the number of patients participating in clinical trials. IRROG’s vision is to double the number of patients accessing clinical trials in line with the Irish National Cancer Strategy target of 6% of cancer patients on clinical trials. Material/Methods: IRROGs work packages included establishing the IRROG group, developing Irish investigator-initiated trials (IIT) and diversifying the portfolio of international academic and combined modality trials. A PPI induction programme was developed to ensure the patient voice is embedded in all trial activity from point of concept design. Monthly national operations meetings with radiotherapy research staff facilitated collaboration between sites, improving trial start-up efficiency. Quarterly “Think In” meetings enabled development of IIT proposals for specific tumour