ESTRO 2025 - Abstract Book
S2830
Physics - Dose prediction, optimisation and applications of photon and electron planning
ESTRO 2025
Conclusion: We have demonstrated a plan optimization method using a TCP model for ENI. It results in inhomogeneous dose distributions, which allow for clinically relevant reductions in OARs doses with small compromise in tumour control.
Keywords: TCP, NTCP, Treatment Planning Optimization
References: 1) Roman Ludwig et.al. A hidden Markov model for lymphatic tumor progression in the head and neck. Scientific Reports, 11(1):12261, June 2021. ISSN 2045-2322. doi: 10.1038/s41598-021-91544-1. Number: 1 Publisher: Nature Publishing Group 2) Paul Okunieff et.al. Radiation dose-response of human tumors. International Journal of Radiation Oncology*Biology*Physics, 32(4):1227–1237, 1995. ISSN 0360-3016. doi: https://doi.org/10.1016/0360 3016(94)00475-Z 4) Lisa Van den Bosch et.al. Comprehensive toxicity risk profiling in radiation therapy for head and neck cancer: A new concept for individually optimised treatment. Radiotherapy and Oncology, 157:147–154, April 2021. ISSN 0167 8140. doi: 10.1016/j.radonc.2021.01.024
Made with FlippingBook Ebook Creator