ESTRO 2025 - Abstract Book

S292

Brachytherapy – Head & neck, skin, eye

ESTRO 2025

Conclusion: The systematic literature review showed that both PDR and HDR BT result in median LC > 92% for lip and nasal vestibule carcinomas. Therefore, a transition from PDR to HDR BT is not expected to influence oncological results. In terms of practical aspects, there are more differences between PDR and HDR. Interview results show that HDR is more flexible than PDR in terms of patient hospitalization and afterloader availability. However, the choice for PDR or HDR is mostly dependent on institutional resources.

Keywords: PDR BT, HDR BT, head and neck carcinoma

References: [1] Guinot, J. L., Arribas, L., Tortajada, M. I., Crispín, V., Carrascosa, M., Santos, M., Mut, A., Vendrell, J. B., Pesudo, C., & Chust, M. L. (2013). From low-dose-rate to high-dose-rate brachytherapy in lip carcinoma: Equivalent results but fewer complications. Brachytherapy, 12(6), 528–534. [2] Guinot, J. L., Strnad, V., & Van Limbergen, E. (2019). The GEC ESTRO Handbook of Brachytherapy - ch.11: Lip and buccal mucosa (2nd edition - 2019). [3]Page, M. J., McKenzie, J. E., Bossuyt, … Moher, D. (2021). The PRISMA 2020 statement: An updated guideline for reporting systematic reviews. In The BMJ (Vol. 372). BMJ Publishing Group.

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Proffered Paper OSIRIS-Nose: Organ Sparing using Interventional Radiotherapy (Brachytherapy) for Invasive Squamous cell cancer of the Nasal Vestibule Tamer Soror 1 , Pierre-Alexander Justenhoven 1 , Warren Bacorro 2 , Dirk Rades 1 , Karl-Ludwig Bruchhage 3 , Anke Leichtle 3 , György Kovács 4 1 Radiation Oncology Department, University of Lübeck/UKSH-CL, Lübeck, Germany. 2 Radiation Oncology Department, Benavides Cancer Institute, University of Santo Tomas Hospital, Manila, Philippines. 3 Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck/UKSH-CL, Lübeck, Germany. 4 Gemelli INTERACTS, Università Cattolica del Sacro Cuore, Rome, Italy Purpose/Objective: Squamous cell carcinoma of the nasal vestibule (SCCNV) is a rare form of cancer, with radical surgery regarded as the standard treatment. However, this can lead to significant functional and aesthetic complications. This analysis investigates an alternative treatment strategy combining high-dose-rate interventional radiotherapy (HDR-IRT, brachytherapy) with organ-preserving surgery.

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