ESTRO 2025 - Abstract Book

S3719

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2025

Conclusion: Esophageal V 55Gy lead to valid prediction in a wide range of diverse treatment techniques and patient characteristics. The generalizability of VBA findings related to RE to an independent cohort of NSCLC patients were successfully demonstrated, thus providing valuable hints for a clinical validation of specific VBA results.

Keywords: Radiation-induced esophagitis, NTCP, validation

References: 1. Monti S, et al. Radiation-Induced Esophagitis in Non-Small-Cell Lung Cancer Patients: Voxel-Based Analysis and NTCP Modeling. Cancers (Basel). 2022;14(7):1833 2. Bradley JD, et al. Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study. Lancet Oncol. 2015;16(2):187-99 3. Palma G, et al. Technical note: MAMBA-Multi-pAradigM voxel-Based Analysis: A computational cookbot. Med Phys. 2023;50(4):2317-2322. 4. Palma G, et al., Voxel-based analysis in radiation oncology: A methodological cookbook. Phys Med. 2020; 69:192 204.

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Poster Discussion Brain tumor perfusion results in a treatment planning system for the open science initiative for perfusion imaging DCE challenge Teo Asplund 1 , Alicia Palmér 1 , Andrew Elliott 2 , Bikash Panthi 3 , Vishantan Kumar 2 , Ashi Chakresh Jain 2 , Stina Svensson 1 , Caroline Chung 2 1 Research, RaySearch Laboratories AB, Stockholm, Sweden. 2 Radiation Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, USA. 3 Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, USA