ESTRO 2025 - Abstract Book

S4048

RTT - Patient care, preparation, immobilisation and IGRT verification protocols

ESTRO 2025

References: 1. Bouchart C, et al. Isotoxic high-dose SBRT for pancreatic cancer. Ther Adv Med Oncol. 2021. doi:10.1177/17588359211045860. 2. Burkoň P, et al. SBRT for pancreatic cancer review. Biomedicines. 2022. doi:10.3390/biomedicines10102480. 3. Grimbergen G, et al. Tumor motion in MR-guided radiotherapy. Phys Imaging Radiat Oncol. 2022. doi:10.1016/j.phro.2021.12.001. 4. Akimoto M, et al. Tumor motion due to respiration. Int J Radiat Oncol Biol Phys. 2017. doi:10.1016/j.ijrobp.2017.03.042. 5. Bouchart C, et al. mFOLFIRINOX, Gemcitabine, SBRT in pancreatic cancer: phase II trial. BMC Cancer. 2023. doi:10.1186/s12885-023-11327-x.

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Digital Poster The use of open-face masks and maskless surface guided radiotherapy for patients undergoing head and neck or brain radiotherapy: A systematic review Megan L Sharkey Department of Radiotherapy and Oncology, James Cook University Hospital, Middlesbrough, United Kingdom Purpose/Objective: Accurate delivery of radiotherapy for head and neck (HN) and brain cancers relies on the use of sophisticated immobilisation devices, usually using a restrictive thermoplastic mask covering the face, head, neck and shoulders. These masks can cause significant patient anxiety and can make treatment difficult, or even unbearable for some patients, particularly those with existing anxiety disorders or claustrophobia. Advances in HN and brain radiotherapy should focus on the introduction of novel immobilisation devices which are as effective as the current standard full-head (FH) masks, without triggering anxiety. Open-face (OF) masks and maskless SGRT have been proposed as novel immobilisation methods for HN and brain radiotherapy to reduce patient anxiety. This review aimed to explore the effectiveness of these immobilisation methods. To date, no full systematic review regarding the translational and rotational set-up errors and intrafractional motions using OF masks and maskless SGRT has been published. Material/Methods: A systematic review was conducted following the recommended PRISMA guidelines. Abstract, title and keyword fields were searched in Scopus, PUBMED, Web of Science and OVID online databases for studies assessing the set up accuracy and intrafractional motion restriction of OF masks or maskless SGRT. Studies were assessed against pre-defined inclusion and exclusion criteria and quality assessment of included studies was performed using the Cochrane RoB-2 and ROBINS-I tools. Quantitative data regarding the translational and rotational set-up errors and intrafractional motions were extracted from included studies and displayed in data tables. Results: Ten studies were identified for inclusion. Four main outcomes of interest were identified: translational set-up errors, rotational set-up errors, translational intrafractional motion, and rotational intrafractional motion. Extracted data suggest that set-up accuracy and immobilisation are similar when using FH masks, OF masks, and maskless SGRT. OF masks can reproduce patient set-up with an accuracy of <2mm and <1° and can restrict patient movement to within 1mm and 0.4°, while maskless SGRT can restrict patient movement to within 0.05mm and 0.1°. Furthermore, this review found that participant experience tended to be more positive with the use of novel immobilisation techniques compared to the traditional FH mask.