ESTRO 2025 - Abstract Book

S815

Clinical - Gynaecology

ESTRO 2025

References: 1. Kirchheiner K, Zaharie A, Smet S, Spampinato S, Chargari C, Haie-Meder C, Mahantshetty U, Šegedin B, Bruheim K, Rai B, Cooper R, Van der Steen-Banasik E, Wiebe E, Pötter R, Sturdza A, Schmid MP, Tanderup K, De Leeuw A, Jürgenliemk-Schulz IM, Nout RA; EMBRACE Collaborative Group. Association Between the Regular Use of Vaginal Dilators and/or Sexual Activity and Vaginal Morbidity in Locally Advanced Cervical Cancer Survivors: An EMBRACE-I Study Report. Int J Radiat Oncol Biol Phys. 2024 Sep 14:S0360-3016(24)03370-4. 2. Jensen PT, Froeding LP. Pelvic radiotherapy and sexual function in women. Transl Androl Urol. 2015 Apr;4(2):186 205. doi: 10.3978/j.issn.2223-4683.2015.04.06. PMID: 26816824; PMCID: PMC4708128.

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Digital Poster Impact of adjuvant radiotherapy on fatigue in gynaecological cancer patients: a 20-years single institutional experience in 501 patients Paolo Bonome 1 , Savino Cilla 2 , Mariangela Boccardi 1 , Mara Fanelli 3 , Marica Ferro 1 , Donato Pezzulla 1 , Vincenzo Picardi 1 , Carmela Romano 2 , Noemi Amore 1 , Milly Buwenge 4 , Alessio Giuseppe Morganti 5,4 , Francesco Deodato 1,6 , Gabriella Macchia 1 1 Radiation Oncology Unit, Responsible Research Hospital, Campobasso, Italy. 2 Medical Phisics Unit, Responsible Research Hospital, Campobassi, Italy. 3 Research laboratories, Responsible Research Hospital, Campobasso, Italy. 4 Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-Bologna University, Bologna, Italy. 5 Radiation Oncology, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy. 6 Istituto di Radiologia, Università Cattolica del Sacro Cuore, Roma, Italy Purpose/Objective: This study evaluated the impact of radiotherapy (RT) on fatigue in patients with gynecological cancer (GC), a common symptom that affects physical and psychological health. Material/Methods: A retrospective evaluation was conducted on GC patients undergoing radical treatment between December 2002 and September 2022. Characteristics such as age, comorbidities, total RT dose, and related toxicities were recorded. Fatigue levels were measured using the Cancer Linear Analogue Scale (CLAS) in three areas: quality of life (CLAS1), energy level (CLAS2), and ability to perform daily activities (CLAS3). Data were collected before RT (T0), after one month (T1), and after 12 months (T2). Two Scores (ScRT10 and ScRT20) were obtained by subtracting the CLAS values at T1 and T2 from the T0 values. A decrease of ≥2 points was considered clinically significant.