ESTRO Brachytherapy for Prostate Cancer 2018

Normal tissue effects and injury – late effects LDR prostate brachytherapy - urothelium

Chronic effects symptoms

findings

management

urothelium

irritative and obstructive symptoms persisting for over 1 year

Rigid, ischaemic tissue, ulceration, telangiectasia, haemorragic epithelium, fibrotic distortion, friable atrophic tissue, necrosis fistula, stricture,

Dr Jeff Glocer

Chronic Inflammation +/- oedema, ulceration, telangiectasia, fibrosis, ischaemia

• Burning • urgency • frequency • nocturia

• urge incontinence • urinary retention • haematuria • spasmodic pain

perforation, obstruction