ESTRO Multidisciplinary Management of Breast Cancer 2017

What to do in case of involved margins ?

What in case of more than focally involved margins ?

 Re-excision:

• > 50% of patients: tumor is found in the re-excision specimen [ Schnitt et al, 1987; Gwin et al, 1993; Kearny et al 1995; Schmidt-Ullrich et al 1995, Merill et al, 2016].

• Risk on finding a lot of residual disease especially high in case of EDCIS (67%), multinodular disease, or diffuse invasive lobular ca (50%) [ Schnitt et al, 1987]