ESTRO PT 2018

Prospective Comparison of Outcomes in Prostate Cancer Patients Treated with Photons or Protons-a proposal to PCORI • Published outcomes with proton therapy appear to show higher disease control rates, lower toxicity rates, and improvement in selected patient reported outcomes than photon based radiation (IMRT) (Mendenhall, 2014 Int J Radiat Oncol Biol Phys; Bryant, 2016 Int J Radiat Oncol Biol Phys) • In addition, hypofractionation (shorter regimens) may be safer and more effective with protons than photons (Henderson, 2017 Acta Oncol; Lee, 2016 J Clin Oncol)