ESTRO 37 Abstract book

radiotherapy weren’t included before seminar number four, because we wanted the attending group of patients to be as homogeneous as possible. The results report of better “good global health” 12 months after seminar- day, compared with data registered before attending the seminar. Results concerning the degree of “good coping skills” are more inconclusive. Only patients participating on seminar nr.2 report an improvement concerning “good coping skills” at 12 month follow up. Nevertheless, the overall results from seminar nr.1-3 concerning “good coping skills” are good.

patients who wanted it. At the first consultation the oncologists asks the patients about their smoking habits. If the patient smokes, the patient receives information about the benefits of quitting. In addition, patients are offered the smoking cessation package. Throughout the course of treatment the patients are followed up with questions about their smoking habits by radiation therapists and nurses. Results The last two years we have handed out about 200 smoking cessation packages and our experience is that a lot of patients are able to quit smoking. Patients are motivated to quit smoking when the information is concrete and objective. Patients need to get information about why it is important to quit smoking during treatment. This is something the patients themselves can do to increase their chances of long-time survival, less side effects and increased quality of life during and after cancer treatment. The project have patient value for cancer patients who smoke because the effect of smoking cessation is high. The project has resulted in a national multi-center project being carried out in collaboration with the Cancer Society and the Norwegian Institute of Public Health. This project started in the autumn of 2017 and is a project that will last two years and the results will be presented in 2019 or 2020. Conclusion Additional information and smoking cessation packages used to motivate cancer patients to quit smoking is a project that provides patient value and requires little resources. We are pleased that the project is now expanding and becoming a national project. EP-1098 Association of XRCC1 polymorphism with laryngeal SCC & with treatment response to chemoradiation V. Raturi 1 1 kokilaben dhirubhai ambani hospital, Radiation oncology, mumbai, India Purpose or Objective To study “Association of XRCC1 Arg914Trp polymorphism with locally advanced laryngeal SCC and with treatment response to chemo-radiation”. Material and Methods A hospital-based case control study was conducted. DNA Isolation and Genotype Analysis is done for cases and control to see for XRCC1 Arg914Trp polymorphism and the treatment response in cases . Odds ratio (OR) with 95% confidence intervals (CI) was computed to estimate the strength association. Results The prevalence of hetero & mutant phenotypes was higher in cases when compared with the controls, which results in statistically significant increase in risk of laryngeal cancer associated with hetero phenotype of XRCC-1 & the mutant phenotype. Increase in risk associated with XRCC-1 hetero and mutant phenotype was seen with smoking, tobacco chewing and alcohol consumption and it was statistically significant. XRCC-1 hetero genotype and mutant genotype frequencies were higher in cases when compared to the controls with a history of smoking, tobacco chewing and alcohol intake. In our study, patients carrying XRCC1 G/G (wt) genotype showed enhanced sensitivity to CRT. Electronic Poster: RTT track: Education and training/role development

Conclusion Providing patients and relatives good information before, and during radiation treatment, will have significant influence on the patient’s perception of their feeling of “good global health”. Arranging seminars with an interdisciplinary professional program seems to be an adequate method preparing and informing prostate cancer patients. The results so far show that our seminar has less influence on patients feeling of “good coping skills”, which we assume may be a direct consequence to both short term- and long term side effects. EP-2395 smoking cessation package for cancer patients who smoke. Help for self-help P.E. Tødenes 1 , I. Kirkhorn 2 1 Ålesund Hospital, Academic Physics, Ålesund, Norway 2 Helse Møre og Romsdal HF, Cancer departement, Ålesund, Norway Purpose or Objective In Norway it is about 33,000 cancer incidents each year. About 12% of Norway's population is smokers. We do not have national data on how many patients are smokers when they get diagnosed with cancer. The consequences of smoking during treatment are more serious than presumed. This applies to radiation therapy, chemotherapy and surgery. Smoking during treatment may result in a lower effect of treatment, more side effects of treatment, increased chance of recurrence and greater chance of relapse. It is important to provide information and knowledge about this to patients so they have the opportunity to quit smoking before treatment. In 2016, we started the smoking cessation project in our department. A smoking cessation package with information brochure and various smoking cessation products was prepared. The goal was to get cancer patients who are smokers, smoke-free before their start In our region, 1720 people were diagnosed with cancer by 2015. To gain focus on this subject we actively used the media and referred to the latest research to inform the people in our region. A smoking cessation package was prepared. It contains an information brochure about the benefits to quit smoking, a list of smoking cessation courses in our region, smoking cessation products such as nicotine tablets, chewing gum, plasters, etc. The smoking package was made by us and given free to the of cancer treatment. Material and Methods