ESTRO 37 Abstract book

S172

ESTRO 37

Abstract text Translational research is the application of basic science findings to improve clinical care. The process of translating basic scientific discoveries to clinical applications, and ultimately to public health improvements is an exciting noble aim. However, it is usually a long journey and most often unsuccessful. There are many steps along the way that need to be taken to assure quality science, but none of them guarantee success. Investigators need to have a hypothesis, they need to have a clear idea what biological questions they are trying to answer. With that, they can design the trial/experiment carefully with the right controls. Cross- disciplinary and cross-organizational communication is a key player in planning these trials. OC-0328 Giving the next generation of Radiation Oncologists a voice - experiences from the young DEGRO C. Ostheimer 1 , N. Ebert 2 1 martin luther university halle-wittenberg, radiation oncology, halle, germany 2 carl gustav carus university dresden, department of radiotherapy and radiation oncology, dresden, germany Purpose or Objective Compared to major clinical specialties such as Internal Medicine or Surgery, Radiation Oncology (RO) can be considered a smaller subject. As such, it has to put particular more interest and emphasis on attr acting young professionals to successfully prepare and provide the next generation of Radiation Oncologists. This is to outline the approach of the German Society of Radiation Oncology (DEGRO) in fostering and supporting the young generation of Radiation Oncologists, Physicists and Biologists and to provide examples of successfully accomplished milestones of the “young DEGRO” working group (yDEGRO). Material and Methods In 2014, the yDEGRO was established as an active working group of young professionals from clinical RO, radiation biology and physics with the aim of providing a development platform for the young RO generation. The main activities of the yDEGRO are 1st to actively and continuously involve young academics in the regular national society meetings, 2nd to create a national collaborative research network with and for young professionals and 3rd to optimize RO resident training in Germany. Results Since the yDEGRO was founded, continuous activities in the national society meetings, which include, for example, own scientific sessions, refresher courses specifically for young professionals, co-chairing of scientific sessions and abstract evaluation, have evolved into a constant successful element of the annual meeting, This increasingly attracts young professionals. So far the yDEGRO has conducted two national surveys about (1) the situation of young RO professionals in Germany, outlining their expectations for our subject, and (2) the quality of RO resident training in Germany. The survey resultsshowed an excellent working atmosphere, a high level of satisfaction and knowledge among German RO residents. Finally, the yDEGRO successfully de novo established a national research network of young academics in RO, including 17 university RO centers in Germany. With the NCT03055715 trial, this research network already developed, designed and carried out their own pioneer multicenter research project with support of the DEGRO and the German Cancer Society / ARO. Recently, this collaborative clinical research project was expanded to include cooperation partners across Europe (Belgium, Switzerland, Spain, United Kingdom). In summa, the increasing activities and popularity of the yDEGRO

improved the perception of the national society and led to significantly increased memberships of young professionals. Conclusion Establishing, promoting and supporting a young academics group within a national society and enabling young professionals to actively participate in the societies´ can not only generate scientific value but also increase the attractivity of the specialty with positive effects on the societies´ general perception and on recruiting young professionals. OC-0329 Predictive value of GTV in radiotherapy of NSCLC - early results of the NCT03055715 trial C. Ostheimer 1 , C. Baues 2 , R. Baumann 3 , C. Billiet 4 , S. Dobiasch 5 , N. Ebert 6 , D. Fleischmann 7 , T. Gauer 8 , Y. Goy 8 , J. Haussmann 9 , C. Henkenberens 10 , L. Kaessmann 11 , J. López guerra 12 , D. Kaul 13 , D. Krug 14 , M. Maeurer 15 , M. Niyazi 16 , M. Oertel 17 , C. Panje 18 , L. Sautter 19 , D. Schmitt 14 , C. Suess 20 , M. Trommer-Nestler 21 , S. Ziegler 22 , D. Medenwald 1 1 university hospital halle, department of radiation oncology, halle, germany 2 university hospital of cologne, department of radiotherapy, cologne, germany 3 university medical center schleswig-holstein, department of radiation oncology, kiel, germany 4 katholieke universiteit leuven, department of radiation oncology, antwerp, belgium 5 technische universität münchen, department of radiation oncology, munich, germany 6 university medical center dresden, department of radiation oncology, dresden, germany 7 lmu munich, department of radiation oncology, munich, germany 8 university medical center hamburg-eppendorf, department of radiotherapy and radio-oncology, hamburg, germany 9 university medical center düsseldorf, department of radiation oncology, düsseldorf, germany 10 hannover medical school, dept. Of radiation oncology, hannover, germany 11 university of schleswig-holstein- campus luebeck, department of radiation oncology, luebeck, germany 12 hospital universitario virgen del rocío, department of radiation oncology, sevilla, spain 13 charité school of medicine and university hospital, department of radiation oncology, berlin, germany 14 university hospital heidelberg and national center for radiation research in oncology ncro and heidelberg institute for radiation oncology hiro, department of radiation oncology, heidelberg, germany 15 university medical center jena, department of radiation oncology, jena, germany 16 lmu munich, department of radiation oncologz, munich, germany 17 university medical center muenster, department of radiation oncology, muenster, germany 18 kantonsspital st. gallen, department of radiation oncology, st. gallen, switzerland 19 university medical center mannheim, department of radiation oncology, mannheim, germany 20 university medical center regensburg, department of radiation oncology, regensburg, germany 21 university hospital of cologne, department of radiation oncology, cologne, germany 22 university medical center erlangen, department of radiation oncology, erlangen, germany Purpose or Objective In the radical radiochemotherapy (RCT) of inoperable non-small-cell lung cancer (NSCLC), typical prognostic factors include T- and N-stage while there is still uncertainty and conflicting data on the prognostic