ESTRO 37 Abstract book

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ESTRO 37

Material and Methods Based on a literature review we defined the margins to be added to the Gross Tumor Volume to include sub- clinical and microscopic disease. This primary tumor CTV was merged to the nodal CTV, as defined in our previous analysis, to define the final CTV Results An atlas showing the defined CTV was generated on reference CT images illustrating the CTV for intra- hepatic, extra-hepatic, and gallbladder cancers (Figure 1)

Conclusion In our experience, SBRT for pancreatic tumour is a feasible and well-tolerated treatment. As neoadjuvant treatment, increase tumour- free margins surgeries in borderline and locally advanced stages. Most patients are free from local progression. The benefit of survival will be evaluated with longer FU. EP-1430 Biliary cancer definitive radiotherapy: an atlas for ctv definition with elective nodal irradiation S. Bisello 1 , L. Calculli 2 , M. Renzulli 2 , G. Sallustio 3 , G. Macchia 4 , F. Deodato 4 , G.C. Mattiucci 5 , S. Cilla 6 , S. Mignogna 7 , V. Picardi 4 , A. Guido 1 , L. Giaccherini 1,8 , A. Arcelli 1,9 , G. Siepe 1 , M. Buwenge 1 , S. Cammelli 1 , V. Valentini 5 , A.G. Morganti 1 1 Radiation Oncology Center, Department of Experimental- Diagnostic and Specialty Medicine - DIMES- University of Bologna, Bologna, Italy 2 Radiology Unit, Department of Diagnostic and Preventive Medicine- S. Orsola-Malpighi Hospital, Bologna, Italy 3 Radiology Unit, Fondazione di Ricerca e Cura “Giovanni Paolo II”, Campobasso, Italy 4 Radiotherapy Unit, Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy 5 Department of Radiation Oncology, Sacred Heart Catholic University of Rome, Rome, Italy 6 Medical Physics Unit, Fondazione di Ricerca e Cura “Giovanni Paolo II”, Campobasso, Italy 7 Medical Oncology Unit, Fondazione di Ricerca e Cura “Giovanni Paolo II”, Campobasso, Italy 8 Radiation Oncology Unit, Department of Oncology and Advanced Technology, Arcispedale S. Maria Nuova-IRCCS of Reggio Emilia, Italy 9 Radiotherapy Department, Ospedale Bellaria, Bologna, Italy Purpose or Objective Radiotherapy (RT) is a treatment option for advanced biliary tumors, generally combined with sequential and/or concurrent chemotherapy. The use of modern RT techniques requires accurate definition of the Clinical Target Volume (CTV). We recently proposed guidelines to define the nodal CTV in these neoplasms (Marinelli I, et al, 2017). Aim of this study was to propose a CT atlas for CTV definition of biliary tumors candidates to exclusive RT

Conclusion This atlas can be an aid for biliary tumors CTV definition and a starting point to design prospective studies on RT in these neoplasms EP-1431 A systematic review on neoadjuvant chemoradiation in resectable pancreatic carcinoma A. Guido 1 , L. Ronchi 1 , I. Calabrese 1 , I.V. Mascia 1 , F. Bertini 1 , A. Arcelli 1,2 , G. Siepe 1 , L. Giaccherini 1,3 , G. Macchia 4 , F. Deodato 4 , S. Cilla 5 , G.C. Mattiucci 6 , V. Picardi 4 , S. Mignogna 7 , A. Di Paolo 7 , M. Buwenge 1 , S. Cammelli 1 , 1 Radiation Oncology Center, Department of Experimental- Diagnostic and Specialty Medicine - DIMES- University of Bologna, Bologna, Italy 2 Radiation Oncology Unit, Bellaria Hospital, Bologna, Italy 3 Radiation Oncology Unit, Department of Oncology and Advanced Technology, Arcispedale S. Maria Nuova-IRCCS of Reggio Emilia, Italy 4 Radiotherapy Unit, Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy 5 Medical Physics Unit, Fondazione di Ricerca e Cura "Giovanni Paolo II", Campobasso, Italy 6 Department of Radiation Oncology, Sacred Heart Catholic University of Rome, Rome, Italy 7 Medical Oncology Unit, Fondazione di Ricerca e Cura “Giovanni Paolo II”, Campobasso, Italy Purpose or Objective Interest for neoadjuvant therapy in resectable pancreatic cancer (PC) is growing due to the disappointing results of