Haematology 2018

Does RT and anti-PD1 leads to generation of systemic anti-tumour immune responses ?

2 5 0 0 0

*

2 0 0 0 0

**

1 5 0 0 0

*

*

**

1 0 0 0 0

*

5 0 0 0

P D -L 1 e x p re s s io n o n C D 4 5 - tu m o u r c e lls

0

7 2 h r

7 2 h r

7 2 h r

7 2 h r

2 4 h r s

2 4 h r s

2 4 h r s

2 4 h r s

7 d a y s

7 d a y s

7 d a y s

7 d a y s

A

B

A

B

N o n T re a te d

5 x 2 G y R T +  P D -1 m A b

Dovedi et Clin Cancer Res 2017